Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Genistein, Soybean
A cell-permeable, reversible, substrate competitive inhibitor of protein tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 = 2.6 μM).
MilliporeSigma™ Calbiochem™ Formin FH2 Domain Inhibitor, SMIFH2
The Formin FH2 Domain Inhibitor, SMIFH2, also referenced under CAS 340316-62-3, controls the biological activity of Formin FH2 Domain. This small molecule/inhibitor is primarily used for Membrane applications.
MilliporeSigma™ Calbiochem™ Adenosine A1 Receptor Agonist I, CPA
A potent and selective agonist of adenosine A1 receptor (A1R) (Ki
MilliporeSigma™ Calbiochem™ Pravastatin, Sodium Salt
A water-soluble, competitive 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that potently blocks in vivo cholesterol synthesis (Ki = ≈1 nM).
MilliporeSigma™ Calbiochem™ Protease Arrest™ Reagent
An optimized concentration of various reversible and irreversible inhibitors to inhibit serine, cysteine, and calpain proteases.
MilliporeSigma™ Calbiochem™ Hexokinase II Inhibitor II, 3-BP
The Hexokinase II Inhibitor II, 3-BP, also referenced under CAS 1113-59-3, controls the biological activity of Hexokinase II. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Nifuroxazide
A cell-permeable and orally available nitrofuran-based antidiarrheal agent that effectively suppresses the activation of cellular STAT1/3/5 transcription activity.
MilliporeSigma™ Calbiochem™ Cdk1 Inhibitor, CGP74514A
The Cdk1 Inhibitor, CGP74514A, also referenced under CAS 190654-01-4, controls the biological activity of Cdk1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ HIF-1α Translation Inhibitor, KC7F2
The HIF-1α Translation Inhibitor, KC7F2, also referenced under CAS 927822-86-4, controls the biological activity of HIF-1α. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Spautin-1
A quinazolin compound that acts as a specific and potent inhibitor of autophagy and promotes Vps34 PI 3-kinase complex degradation by blocking the activity of USP 10 (IC50 = 580nM) and USP 13 (IC50 = 690nM) deubiquitinating enzymes
MilliporeSigma™ Calbiochem™ MARK/Par-1 Activity Inhibitor, 39621
The MARK/Par-1 Activity Inhibitor, 39621 controls the biological activity of MARK/Par-1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Amiloride, Hydrochloride
An inhibitor of angiogenesis.
MilliporeSigma™ Calbiochem™ JNK Inhibitor II
JNK Inhibitor II. SP600125, CAS 129-56-6, is a potent, cell-permeable, selective, and ATP competitive inhibitor of c-Jun N-terminal kinase (JNK; IC50 = 40 nM for JNK-1 & JNK-2 & 90 nM for JNK-3).
MilliporeSigma™ Calbiochem™ Phosphatase Inhibitor Cocktail Set III, Lyophilized
The Phosphatase Inhibitor Cocktail Set III, Lyophilized controls the activity of Phosphatase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ ZM 336372
A potent, cell-permeable, reversible, ATP-competitive and specific inhibitor of the protein kinase c-Raf (IC50 = 70 nM).